Costs a decent bit more to make the offset rim bed (in terms of the huge tooling that extrudes/forms the aluminum), and the spoke drilling can be janky. The WTB Asyms also have the non-offset valve hole, which looks odd but in practice is a non-issue.
With rim widths settling into the 25-35mm range for most applications, being able to get 2.5-4mm of offset, coupled with wider flanges on hubs (especially on the back) mean that having wildly different spoke tensions will be a thing of the past, but because this opens up the possiblity for making really low spoke count wheels that won't necessarily implode, we'll see lots of slightly anemic builds sporting impressive weights, but also the ability to spec out fairly classic builds to be really solid (32 spoke F/R, brass nipples, double butted 14/15/14ga j-bend spokes, on offset rims). I think the only reason the market for the latter isn't bigger is that guys (particularly larger and aggressive riders) have already gone out and gotten handbuild wheels meeting those specifications for 15x100/12x142mm hub spacings, and those wheels are still rolling along awesome. The high-bling wheelsets, and cost-target OEM ones get binned a lot quicker, so we see more press about it.
I think the RF Turbine-R (Although TBH, I don't know why they didn't make these the Atlas wheels) will be an eye-opener for a lot of people, because the offset rim on a burly hub with an appropriate specification of the spoke/nipple combination ends up nit being heavy, but will be remarkably rugged. The only downside is that the super-fast engagement hub out back sends the price skyward, and that they're still speccing 28H front and rear, so my corpuscular self would still likely get an untimely hankering for tacos if I ran them too hard.