For me at my weight and the way I ride (LOTS of time riding in Moab, which is hard on tires and rims - though I've never had a problem at 160 pounds), inserts aren't needed. I put them in an ebike tire and on my Trance 29 but found several problems.
This is regarding Turbolight SL inserts. First of all, they make the ride harsh. (Specifically in my case. It would help for many people if you're running high pressures to avoid rim strikes - but that's not me) Much like tokens, which can also be useful, they reduce the volume of air in the tire so there's a fast ramp up in pressure.
The inserts aren't compressible as a function of air pressure, just impact, so if you take up half the air space with the insert, only half is available to be compressed. I already run low pressures anyway and have a light touch, I guess. 20+ year of riding the square edged bumps/steps in Utah without ever hitting a rim.
Secondly, in my case after checking on them in a week, I got "stanimals" and that was with Orange Seal! So, with the solids "churned out" of solution, the tires won't seal as well.
Finally, if you do damage a tire past the point of sealant or bacon strips, you now have to remove the tire from the rim to install a tube. I found that to be difficult at home, much less on a trail as the insert presses against the bead holding it in place.