from my own personal experience, i would say that it really depends on whether you factor disc brakes into the equation of upgrading and whether your current frame / forks have disc brake mounts.
If you dont want discs, then yes, it can be worth upgrading the componenty to get nicer parts and wheels.
If you do intend to use disk brakes and the frame cant handle it, then sometimes, it would be worth teh jump to a complete new bike with the discs already there.
I have an old fisher frame and the only thing thats left is the frame . . . but my biggest bug bear has been the lack of a disc mount on the rear. So finally, i've just bought a second hand Klein frame with a rear disc mount to address this issue.
If you dont want discs, then yes, it can be worth upgrading the componenty to get nicer parts and wheels.
If you do intend to use disk brakes and the frame cant handle it, then sometimes, it would be worth teh jump to a complete new bike with the discs already there.
I have an old fisher frame and the only thing thats left is the frame . . . but my biggest bug bear has been the lack of a disc mount on the rear. So finally, i've just bought a second hand Klein frame with a rear disc mount to address this issue.