I think it depends on a few things fitness, where you live(terrain), and how long the climbs are. I run 34:18 where I live in and would gear to 34:20 for bigger days with sustained climbing like a 30mi 4k day with the grade of climbs around me. For endurance racing like 8 hours I have typically run 32:20/21 depending on climbing and for short track stuff i used to run 35:16. I have a friend and he is typically 2 teeth higher so 36:16 typically all the time and he is a masher top age group nationally type guy for mtb for reference. I tend to gear to ride as much as possible and for as long as possible and the 2:1 plus a tooth or two gets me there for daily driving.