i22 is just fine for 2.1/2.2, but my preference would be i24. I recently built up a wheelset with i26 rear, i27 front for use with 2.25-2.4 tires (currently running 2.35 front and rear). I have another bike with 2.25 on i30 and I actually prefer that but as you said I'm not sure it's worth the weight.
Using the same rotors across wheels will hopefully help with not having to messing with brake alignment but if the wheels have different hubs then there may still be some spacing differences. I use a single cassette per bike and just move it between wheelsets when changing.
Using the same rotors across wheels will hopefully help with not having to messing with brake alignment but if the wheels have different hubs then there may still be some spacing differences. I use a single cassette per bike and just move it between wheelsets when changing.