Being a 350 plus clyde, I can honestly say there are extra rules for us. Now I have heard frame this and frame that....that's fine but I've broken some expensive parts in the past few years. My latest one was Shimano's SLX cranks and SLX shifters. One rule I have is.....unless you plan on going XTR or Race Face or some other 3rd party besides shimano, avoid the upper middle of shimano as much as possible. I have had some older LX and XT cranks in the past but they were heavier. However they were stronger. Nowdays I recommend for clyde in staying with XTR or Deore. They seem stronger than the ones between them. Even my Deore shifters on my commuter were better than the SLX. Also, Make sure your hubs are up to par that can handle your weight. For me, the WTB Speed Disk won this battle for value and price. I have friends that are clydes and they said their LX and SLX needed a repack about everyother ride. But I just think they are using cheap bearings.