First up, which rims are these, the older symmetrical or the newer asymmetrical? If they're the newer asym rim, then it's going to depend on which wheel you're talking about, front or rear, as the rim will be flipped front to rear so the asym is where it needs to be.
I have a set of the new asym rims and although at first glance the holes may look to be drilled centered, they in fact are not and are slightly off to the side the spoke should go in from, so for the rear, that would mean that the first hole to the left of the valve hole, looking at it from the drive side, goes to the drive side. On the front, it means that spoke goes to the non drive side.