Just outta curiousity, have you tried rotating your handlebars ever so slightly? If it's uneven pressure on your palms, just a few degrees can make all the difference between sweet spot and pressure points.
Oh, FWIW, I found the "blob" or whatever Specialized puts on the palms of their Body Geometry gloves to be rather comfortable, yet I prefer the minimalist, breathable style of the Fox Tahoe gloves.
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