Do you feel like you are stretching to reach the handlebars or are you crunched up in the cockpit? Sitting more upright definitely helps me when I am riding so I tend to use my bar ends when I am just cruising. That may help you a bit as well with a change in stem angle.
I know it can be tough but proper posture is a must for every activity. (I need to follow my own advice more, especially at work!) I would highly suggest working at that.
While I have not experienced any major physical problems with my 18.5" EX8, I have noticed a slight tightening in my lower back and a little more neck stiffness than with my old K2 hardtail. My 2 hour ride Sunday left me feeling pretty good (mainly tired

) but as I mentioned, with just a slight tightness in my lower back and neck. I will have to see how I feel as time goes on but I am initially attributing this to an increase in ride time and adjusting to a new bike. Plus shaking off the winter, desk-job cobwebs.
Even though we are about the same dimensions, I personally went with the 18.5" frame instead of the 19.5" because it felt like I was stretching on the larger one (which now I think could have been adjusted with a shorter stem). But even with the results from
www.competitivecyclist.com, the recommended Tube Top Length for me is 24.1 - 24.5 and the 18.5" EX8 comes in at 24" while the 19.5" is 24.7". So I obviously went smaller, which I hope does not turn out to be a mistake.
In case you were wondering, here are my rough measurements from the same site:
Inseam 34.25 in
Trunk 25.375 in
Forearm 14 in
Arm 27 in
Thigh 24.625 in
Lower Leg 23.25 in
Sternal Notch 58.5 in
Total Body Height 71 in