If its a cup and cone bearing hub...like Shimano hubs then a solid axle is about all you can do. Some sealed bearing hubs allow you to switch out from QR to 20mm up front (of course you'll need a 20mm fork as well).
You have very few options for changing axles in hubs. You're locked in by the dimensions, bearings and clearances in the shell, so while you can replace parts there's little or no room (literally) for improvement. In some cases you might upgrade axles to a better material, or buy higher quality bearings, but it's usually not possible to do more.
The time to consider upgrading your hubs is when something happens to the rim and you need to rebuild or replace the wheel
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