I use slime tubes. They are HEAVY, but i haven't had a flat since i've been using them for the past 3 years. I tried tubeless and the weight savings was nice, but prefer tubes for the simplicity and not having to worry about burping.
I had horrible problems with thorns when I first picked up my 29er since I come from riding dirt bikes where you can ride through any size blackberry bush and never worry about it penetrating the tire/tube. I picked up a set of nylon liners that go between the tube and tire. Haven't got a flat since. Your LBS shop should have some.
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